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What is 'Fetal Fraction' and What Does it Mean for Your Non-Invasive 2015 Sep;126(3):e31-7. The clinical management of women with failed NIPT results due to low FF should include detailed fetal ultrasound examination and an individualized discussion of the available options including diagnostic testing, NIPT redraw, and alternative screening tests. 640: Cell-Free DNA Screening For Fetal Aneuploidy. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Not all low fetal fraction cellfree DNA screening failures are at The reason was because there was a twin which they didnt know about, and that had passed away very early in in the pregnancy. I got low fetal fraction and the 1/17 high risk at 12 weeks with Natera and then retested with MaterniT21 and got normal results with only 3% fetal fraction at around 15 weeks. The key to its success: MaterniT21, a new prenatal screening test that did remarkably well at detecting Down syndrome. This new . But please be reassured of this: NIPT is not 100 percent conclusive. Per a google search, anything less than 3-4% can supposedly be unreliable or picking up certain disorders and gender. I did it last year at around 12-13 weeks and luckily had 4.2% fetal fraction which is enough over the threshold for them Have any of your NIPT gender results turned out to be wrong at your anatomy scan? But I know those won't show a no result. PDF Large scale follow-up research study: SneakPeek Early Gender DNA Test What was your fetal fraction and gender? - What to Expect