Conflict of interest statement: The authors declare that there is no conflict of interest. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work. FOIA Avoid taking an herbal supplement containing St. John's wort. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some people may have hair loss while taking Ofev. Nintedanib comes as a capsule to take by mouth. Nintedanib inhibits the following RTKs: Research has shown that nintedanib starts to improve FVC within 6 weeks of starting the medication. to treat adults with a long-lasting (chronic) interstitial lung disease in which lung fibrosis continues to worsen (progress). Recent real-word studies also suggest that nintedanib stabilizes lung function till lung transplantation, with no increased surgical complications or postoperative mortality after lung transplantation. Drug class: Multikinase inhibitors. If you have any of these problems, talk with your doctor about which highly effective birth control method is right for you. nintedanib experience nausea 18 out of 100 patients on placebo experience rash 62 out of 100 patients on nintedanib experience rash A B How do I take nintedanib (brand name Ofev) and what side effects can occur? Ofev: Uses, Dosage & Side Effects - Drugs.com Its not known if Ofev passes into breast milk. What should I tell my doctor before using Ofev? Unauthorized use of these marks is strictly prohibited. Ofev is available only as a brand-name medication. Do not let anyone else take your medication. -, Ley B, Collard HR, King TE., Jr. Clinical course and prediction of survival in idiopathic pulmonary fibrosis. Accessibility Here are answers to some frequently asked questions about Ofev. Drugs. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Chronic Fibrosing Interstitial Lung Disease With A Progressive Phenotype, Systemic Sclerosis-Associated Interstitial Lung Disease. Do not open the capsules. Licensed from: Boehringer Ingelheim International GmbH. URL of this page: https://medlineplus.gov/druginfo/meds/a615009.html. Tell them about all prescription, over-the-counter, and other drugs you take. and transmitted securely. In clinical trials, diarrhea was the most common side effect reported with Ofev. Epub 2021 Mar 25. It is not known if nintedanib passes into your breast milk. Use effective birth control, with an extra barrier method (condom, diaphragm, cervical cap, contraceptive sponge). Visit www.fda.gov/safety/medwatchor call 1-800-FDA-1088. Mechanism of Action | OFEV (nintedanib) If you think you or someone else may have overdosed on: Ofev (Nintedanib) , call your doctor or the Poison Control center (800) 222-1222 Learn more about the causes, symptoms, and treatment options. Nintedanib Market Recent Developments and Updates By 2030